@article{oai:fujijoshi.repo.nii.ac.jp:00000332, author = {松本, 恵 and 原 博 and MATSUMOTO, Megumi and HARA Hiroshi}, month = {Mar}, note = {Flavonoids are polyphenols that are found in many foods and which function as antioxidants in the body. However, the mechanisms for absorption of polyphenolic compounds remain unclear. The recently-manufactured quercetin glycoside αG-rutin is a water-soluble glucose adduct of rutin (quercetin-3-β-glucosyl-rhamnose) and this compound is 1,000 times dissolubility is higher than rutin. This review describes how the intestinal absorption and metabolism of αG-rutin in vivo, in situ and in vitro. αG-rutin is transported through the intestinal mucosa both in vivo and in vitro, and demonstrated that a considerable proportion of the αG-rutin was absorbed as the intact glycoside via the paracellular pathway. In addition, αG-rutin is absorbed more efficiency than either quercetin or rutin and that a high plasma concentration can be maintained by supplying rutin αG-rutin in combination in in vivo study. Thus, αG-rutin will be an effective source of quercetin and expected to be beneficial as antioxidant for human health., 6, KJ00005073552}, pages = {31--38}, title = {水溶性フラボノイド配糖体αG-ルチンの消化管吸収機構}, volume = {45}, year = {2008}, yomi = {マツモト, メグミ and ハラ, ヒロシ} }