{"created":"2023-06-20T13:41:21.111333+00:00","id":652,"links":{},"metadata":{"_buckets":{"deposit":"28ed331b-2c69-46f7-af74-fadcdd810706"},"_deposit":{"created_by":3,"id":"652","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"652"},"status":"published"},"_oai":{"id":"oai:fujijoshi.repo.nii.ac.jp:00000652","sets":["6:56:59:60"]},"author_link":["900","899","902","901"],"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"10","bibliographicPageStart":"5","bibliographicVolumeNumber":"3","bibliographic_titles":[{}]}]},"item_3_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"メタボリックシンドロームにおいて、もっとも重要な病態は肥満である。肥満は生体が余剰なエネルギーを蓄積していく過程において、脂肪細胞が肥大化し、脂肪細胞数が増加した脂肪組織の過剰状態である。脂肪細胞は脂肪を貯蔵するだけでなく、種々なるアデイポカインを産生、分泌し、重要な生理機能を発揮している。しかしながら、肥満に伴うこれら生理機能の破綻は糖尿病、高血圧、高脂血症、動脈硬化症など生活習慣病の主要な原因となる。この総説では栄養素摂取をめぐって、メタボリックシンドロームと脂肪細胞の関係について論ずる。","subitem_description_type":"Other"}]},"item_3_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The origin of metabolic syndrome is the disordered life style, overeating and lack of exercise, and the accumulation of visceral fat. Namely, obesity is a principal causative factor in the development of metabolic syndrome, a condition that greatly increases the risk of type 2 diabetes, cardiovascular disease and stroke. Adipocytes are not merely storage sites of (fat) triglyceride produced from excessive energy but also secrete various physiologically active substances (adipocytokine) such as tumor necrosis factor-α (TNF-α), resistin, interleukin-6 (IL-6), plasminogen activator inhibitor-1 (PAI-1), adiponectin, and leptin. Dysregulation of adipocytokine secretion in subjects with visceral accumulation such as hypersecretion of PAI-1, TNF-α and hyposecretion of adiponectin may be an important molecular basis of metabolic syndrome. This paper is reviewed on the relationship between metabolic syndrome and adipocytes in nutrients.","subitem_description_type":"Other"}]},"item_3_description_15":{"attribute_name":"表示順","attribute_value_mlt":[{"subitem_description":"5","subitem_description_type":"Other"}]},"item_3_description_16":{"attribute_name":"アクセション番号","attribute_value_mlt":[{"subitem_description":"KJ00006452263","subitem_description_type":"Other"}]},"item_3_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"総説","subitem_description_type":"Other"}]},"item_3_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"General manuscript","subitem_description_type":"Other"}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA12218176","subitem_source_identifier_type":"NCID"}]},"item_3_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"藤女子大学QOL(福祉)研究所 "},{"subitem_text_value":" 藤女子大学人間生活学部食物栄養学科"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Faculty of Human Life Science, Institute of QOL, Fuji Women's University "},{"subitem_text_language":"en","subitem_text_value":" Faculty of Human Life Science, Department of Food Science and Human Nutrition, Fuji Women's University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"坂本, 亘"}],"nameIdentifiers":[{"nameIdentifier":"899","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤井 義博"}],"nameIdentifiers":[{"nameIdentifier":"900","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SAKAMOTO, Wataru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"901","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"FUJII Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"902","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-08-22"}],"displaytype":"detail","filename":"KJ00006452263.pdf","filesize":[{"value":"238.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006452263.pdf","url":"https://fujijoshi.repo.nii.ac.jp/record/652/files/KJ00006452263.pdf"},"version_id":"87bf5abd-e90c-432e-b73e-4844a0ad08eb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"メタボリックシンドローム ","subitem_subject_scheme":"Other"},{"subitem_subject":" 脂肪細胞 ","subitem_subject_scheme":"Other"},{"subitem_subject":" 栄養","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"メタボリックシンドロームと脂肪細胞","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"メタボリックシンドロームと脂肪細胞"},{"subitem_title":"Metabolic syndrome and Adipocyte","subitem_title_language":"en"}]},"item_type_id":"3","owner":"3","path":["60"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-22"},"publish_date":"2016-08-22","publish_status":"0","recid":"652","relation_version_is_last":true,"title":["メタボリックシンドロームと脂肪細胞"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T14:18:04.622175+00:00"}